Igor Dikiy

The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of  -synuclein, and enhances its secretion and nuclear localization in cells

Mohamed-Bilal Fares, Nadine Ait‐Bouziad, Igor Dikiy et al. · Human Molecular Genetics · 2014 · 236 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease

Anne-Laure Mahul-Mellier, Bruno Fauvet, Amanda M. Gysbers et al. · Human Molecular Genetics · 2014 · 220 citations · Full text

Life Sciences, Biochemistry, Neuroscience +16

N-terminal Acetylation Stabilizes N-terminal Helicity in Lipid- and Micelle-bound α-Synuclein and Increases Its Affinity for Physiological Membranes

Igor Dikiy, David Eliezer · Journal of Biological Chemistry · 2013 · 201 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

The H50Q Mutation Enhances α-Synuclein Aggregation, Secretion, and Toxicity

Ossama Khalaf, Bruno Fauvet, Abid Oueslati et al. · Journal of Biological Chemistry · 2014 · 178 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +12

Characterization of Semisynthetic and Naturally Nα-Acetylated α-Synuclein in Vitro and in Intact Cells

Bruno Fauvet, Mohamed-Bilal Fares, Filsy Samuel et al. · Journal of Biological Chemistry · 2012 · 173 citations · Full text

Life Sciences, Biochemistry, Neuroscience +10