Concepedia

Karel Chalupský

KC

45

Publications

2K

Citations

26

H-Index

2002

Active since

Affiliations

Czech Academy of Sciences, Institute of Molecular Genetics(Current)

Charles University

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

Inserm

Centre National de la Recherche Scientifique

Karel Chalupský is an author at Czech Academy of Sciences, Institute of Molecular Genetics specializing in medicine, oxidative stress, and pharmacology.

ORCID

Top concepts

Publications per year

2002–2025

45

Publications

45

Endothelial dihydrofolate reductase: Critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase

Karel Chalupský, Hua Cai · Proceedings of the National Academy of Sciences · 2005 · 334 citations · Full text

Role of Uncoupled Endothelial Nitric Oxide Synthase in Abdominal Aortic Aneurysm Formation

Ling Gao, Kin Lung Siu, Karel Chalupský et al. · Hypertension · 2011 · 114 citations · Full text

Mechanistic insights into folic acid-dependent vascular protection: Dihydrofolate reductase (DHFR)-mediated reduction in oxidant stress in endothelial cells and angiotensin II-infused mice: A novel HPLC-based fluorescent assay for DHFR activity

Ling Gao, Karel Chalupský, Enrico Stefani et al. · Journal of Molecular and Cellular Cardiology · 2009 · 100 citations · Full text

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Delphinidin and cyanidin inhibit PDGF<sub>AB</sub>‐induced VEGF release in vascular smooth muscle cells by preventing activation of p38 MAPK and JNK

M.H. Oak, Jasser El Bedoui, Socorro Vanesca Frota Madeira et al. · British Journal of Pharmacology · 2006 · 94 citations · Full text

KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype

Petr Kašpárek, Zuzana Ileninova, Olga Zbodakova et al. · PLoS Genetics · 2017 · 89 citations · Full text

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