Concepedia

Helen L. Lightfoot

HL

Statistics

Publications

11

Citations

535

H-Index

11

Active since

2008

Affiliations

ETH Zurich(Current)

The Gurdon Institute

University of Cambridge

TU Dortmund University

Helen L. Lightfoot is an author at ETH Zurich specializing in life sciences, molecular biology, and gene expression.

Publications per year

2008–2021

11

Publications

11

LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans

Nicolas J. Lehrbach, Javier Armisen, Helen L. Lightfoot et al. · Nature Structural & Molecular Biology · 2009 · 232 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Synthesis and cellular activity of stereochemically-pure 2′-O-(2-methoxyethyl)-phosphorothioate oligonucleotides

Meiling Li, Helen L. Lightfoot, François Halloy et al. · Chemical Communications · 2016 · 48 citations

Life Sciences, Biochemistry, Molecular Biology +17

A LIN28-Dependent Structural Change in pre-let-7g Directly Inhibits Dicer Processing

Helen L. Lightfoot, Anthony Bugaut, Javier Armisen et al. · Biochemistry · 2011 · 42 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Identification of small molecule inhibitors of the Lin28-mediated blockage of pre-let-7g processing

Helen L. Lightfoot, Eric A. Miska, Shankar Balasubramanian · Organic & Biomolecular Chemistry · 2016 · 38 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +16

Target mRNA inhibition by oligonucleotide drugs in man

Helen L. Lightfoot, Jonathan Hall · Nucleic Acids Research · 2012 · 36 citations · Full text

Pharmacy, Oncology, Pharmacology +12

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