Shigehide Kagaya

NK314, a Topoisomerase II Inhibitor That Specifically Targets the α Isoform

Eriko Toyoda, Shigehide Kagaya, Ian G. Cowell et al. · Journal of Biological Chemistry · 2008 · 104 citations · Full text

Medicine, Oncology, Pharmacology +13

A Functional Role for Death Proteases in s-Myc- and c-Myc-Mediated Apoptosis

Shigehide Kagaya, Chifumi Kitanaka, Kohji Noguchi et al. · Molecular and Cellular Biology · 1997 · 66 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Caspase-dependent apoptosis of COS-7 cells induced by Bax overexpression: differential effects of Bcl-2 and Bcl-xL on Bax-induced caspase activation and apoptosis

Chifumi Kitanaka, Takahiro Namiki, Kohji Noguchi et al. · Oncogene · 1997 · 63 citations

Life Sciences, Cell Biology, Apoptosis +11

NK314, a novel topoisomerase II inhibitor, induces rapid DNA double-strand breaks and exhibits superior antitumor effects against tumors resistant to other topoisomerase II inhibitors

Takeshi Onda, Eriko Toyoda, Osamu Miyazaki et al. · Cancer Letters · 2007 · 36 citations

Medicine, Oncology, Pharmacology +16

Pim-1 kinase stimulates c-Myc-mediated death signaling upstream of caspase-3 (CPP32)-like protease activation

Toshihiro Mochizuki, Chifumi Kitanaka, Kohji Noguchi et al. · Oncogene · 1997 · 35 citations

Life Sciences, Cell Biology, Molecular Biology +16