Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder

Ryan K. C. Yuen, Daniele Merico, Matt Bookman, +80

Nature Neuroscience

Next-generation SequencingGeneticsPsychiatric GeneticsMolecular BiologyAutism +7

Whole-genome sequencing of quartet families with autism spectrum disorder

Ryan K. C. Yuen, Bhooma Thiruvahindrapuram, Daniele Merico, +25

Nature Medicine

SequencingSyndromic AutismNext-generation SequencingGeneticsMolecular Biology +6

Genome-wide characteristics of de novo mutations in autism

Ryan K. C. Yuen, Daniele Merico, Hongzhi Cao, +45

npj Genomic Medicine

GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo

Caroline Pabst, Anne Bergeron, Vincent‐Philippe Lavallée, +17

Blood

SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons

Kirill Zaslavsky, Wenbo Zhang, Fraser P. McCready, +17

Nature Neuroscience

Neurodevelopmental DisordersHuman NeuronsMolecular NeuroscienceNeurophysiologyNeuroanatomy +11

Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

Éric Deneault, Sean H. White, Deivid C. Rodrigues, +20

Stem Cell Reports

A Functional Screen to Identify Novel Effectors of Hematopoietic Stem Cell Activity

Éric Deneault, Sonia Cellot, Amélie Faubert, +7

Cell

MedicineStem Cell MobilizationHematologyIdentify Novel EffectorsStem Cell Research +9

CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks

Éric Deneault, Muhammad Faheem, Sean H. White, +15

eLife

A role for GPx3 in activity of normal and leukemia stem cells

Olivier Hérault, Kristin J. Hope, Éric Deneault, +8

The Journal of Experimental Medicine

Hematological MalignancyGpx3 ShrnaLineage PlasticityDevelopmental BiologyGpx3 Promoter Region +12

Synaptic Dysfunction in Human Neurons With Autism-Associated Deletions in PTCHD1-AS

P. Joel Ross, Wenbo Zhang, Rebecca S.F. Mok, +16

Biological Psychiatry