Osama H. Elshenawy

Cytochrome P450 epoxygenase metabolite, 14,15-EET, protects against isoproterenol-induced cellular hypertrophy in H9c2 rat cell line

Mandy M. Tse, Mona E. Aboutabl, Hassan N. Althurwi et al. · Vascular Pharmacology · 2013 · 45 citations

Molecular Physiology, Biochemistry, Medicine +9

19-Hydroxyeicosatetraenoic acid and isoniazid protect against angiotensin II-induced cardiac hypertrophy

Samya Elkhatali, Ahmed A. El-Sherbeni, Osama H. Elshenawy et al. · Toxicology and Applied Pharmacology · 2015 · 38 citations

Hypertension, Cardiomyopathy, Cardiovascular Disease +9

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms

Anwar Anwar‐Mohamed, Osama H. Elshenawy, Anatoly A. Soshilov et al. · Free Radical Biology and Medicine · 2013 · 33 citations

Chemical Biology, Quinone Oxidoreductase, Aldo-keto Reductase +12

Human fetal ventricular cardiomyocyte, RL-14 cell line, is a promising model to study drug metabolizing enzymes and their associated arachidonic acid metabolites

Zaid H. Maayah, Osama H. Elshenawy, Hassan N. Althurwi et al. · Journal of Pharmacological and Toxicological Methods · 2014 · 33 citations

Cardiomyopathy, Biochemistry, Promising Model +10

Early Changes in Cytochrome P450s and Their Associated Arachidonic Acid Metabolites Play a Crucial Role in the Initiation of Cardiac Hypertrophy Induced by Isoproterenol

Hassan N. Althurwi, Zaid H. Maayah, Osama H. Elshenawy et al. · Drug Metabolism and Disposition · 2015 · 32 citations · Full text