M.T. Hilgers - Concepedia

Author

M.T. Hilgers

Arcturus Therapeutics (United States)ORCID

Also Known As

Hilgers, Mark T., M. Hilgers, M.T. Hilgers, Mark Hilgers, Mark T. Hilgers

Publications

1.4K

Citations

H-Index

Concepts

All Affiliations

Arcturus Therapeutics (United States)Eli Lilly (United States)University of Michigan Hospital Clínico San Carlos

About

M.T. Hilgers is an author at Arcturus Therapeutics (United States) specializing in medicine, biochemistry, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	9	9	501
2	Biochemistry	6	6	494
3	Natural Sciences	5	5	423
4	Engineering	2	2	126
5	Health Sciences	2	2	163

M.T. Hilgers

Publications

1.3K

Citations

H-Index

Page 1

	Year	Citations
Novel Ribosomal Mutations in <i>Staphylococcus aureus</i> Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700) Jeffrey B. Locke, M.T. Hilgers, Karen Joy Shaw Antimicrobial Agents and Chemotherapy	2009	202
Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant <i>Staphylococcus aureus</i> Strains Possessing the <i>cfr</i> Methyltransferase Gene or Ribosomal Mutations Jeffrey B. Locke, John M. Finn, M.T. Hilgers, Antimicrobial Agents and Chemotherapy	2010	145
Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase J.C. Evans, D.P. Huddler, M.T. Hilgers, Proceedings of the National Academy of Sciences Aldo-keto ReductaseBiochemistryFolate SubstratesNatural SciencesBiocatalysis	2004	144
Mutations in Ribosomal Protein L3 Are Associated with Oxazolidinone Resistance in Staphylococci of Clinical Origin Jeffrey B. Locke, M.T. Hilgers, Karen Joy Shaw Antimicrobial Agents and Chemotherapy Oxazolidinone ResistanceAntibiotic AdjuvantGeneticsStaphylococcus AureusMolecular Biology	2009	133
Crystal structure of the quorum-sensing protein LuxS reveals a catalytic metal site M.T. Hilgers, Martha Ludwig Proceedings of the National Academy of Sciences Crystal StructureBioorganic ChemistryEngineeringProtein AssemblyMolecular Biology	2001	107
Conformational Flexibility in Crystal Structures of Human 11β-Hydroxysteroid Dehydrogenase Type I Provide Insights into Glucocorticoid Interconversion and Enzyme Regulation David J. Hosfield, Yiqin Wu, R.J. Skene, Journal of Biological Chemistry Enzyme Active SiteAldehyde DehydrogenaseBiochemistryProtein AssemblyProtein Folding	2004	102
Elevated Linezolid Resistance in Clinical <i>cfr</i> -Positive <i>Staphylococcus aureus</i> Isolates Is Associated with Co-Occurring Mutations in Ribosomal Protein L3 Jeffrey B. Locke, Gracia Morales, M.T. Hilgers, Antimicrobial Agents and Chemotherapy	2010	76
Crystal Structures of Active Fully Assembled Substrate- and Product-Bound Complexes of UDP-<i>N</i>-Acetylmuramic Acid:<scp>l</scp>-Alanine Ligase (MurC) from<i>Haemophilus influenzae</i> Clifford D. Mol, Alexei Brooun, Douglas R. Dougan, Journal of Bacteriology	2003	71
Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7-(Benzimidazol-1-yl)-2,4-diaminoquinazolines Thanh Lam, M.T. Hilgers, Mark L. Cunningham, Journal of Medicinal Chemistry Molecular PharmacologyAntimicrobial Drug DiscoveryBiochemistryAntibioticsMedicine	2014	71
Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines Xiaoming Li, M.T. Hilgers, Mark L. Cunningham, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryMedicineStructure-based DesignAntibacterial AgentAntimicrobial Compound	2011	59

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