Piero Dalle Pezze

A systems study reveals concurrent activation of AMPK and mTOR by amino acids

Piero Dalle Pezze, Stefanie Ruf, Annika Sonntag et al. · Nature Communications · 2016 · 442 citations · Full text

Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions

Piero Dalle Pezze, Glyn Nelson, Elsje G. Otten et al. · PLoS Computational Biology · 2014 · 162 citations · Full text

Aging, Targeted Interventions, Senescence Onset +20

A Dynamic Network Model of mTOR Signaling Reveals TSC-Independent mTORC2 Regulation

Piero Dalle Pezze, Annika Sonntag, Antje Thien et al. · Science Signaling · 2012 · 144 citations

Molecular Regulation, Molecular Biology, Cytoskeleton +20

A modelling–experimental approach reveals insulin receptor substrate (IRS)‐dependent regulation of adenosine monosphosphate‐dependent kinase (AMPK) by insulin

Annika Sonntag, Piero Dalle Pezze, Daryl P. Shanley et al. · FEBS Journal · 2012 · 54 citations · Full text

Increasing extracellular H2O2 produces a bi-phasic response in intracellular H2O2, with peroxiredoxin hyperoxidation only triggered once the cellular H2O2-buffering capacity is overwhelmed

Lewis E. Tomalin, Alison M. Day, Zoe Underwood et al. · Free Radical Biology and Medicine · 2016 · 46 citations · Full text

Lipid Peroxidation, Extracellular H2o2, Cell Death +18