Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives

X Ruan, Ana Pereda, Diane L. Stassi, +8

Journal of Bacteriology

EngineeringMolecular BiologyChemical BiologyMedicinal ChemistryBiosynthesis +15

Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering

Diane L. Stassi, Stephan J. Kakavas, Kevin A. Reynolds, +7

Proceedings of the National Academy of Sciences

Cloning of chromosomal genes in Streptococcus pneumoniae.

Diane L. Stassi, Paloma López, Manuel Espinosa, +1

Proceedings of the National Academy of Sciences

BiosynthesisStreptococcus PneumoniaeAntimicrobial Resistance GenePathogenesisBacteriology +9

Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis

Diane L. Stassi, Stefano Donadio, Michael J. Staver, +1

Journal of Bacteriology

EngineeringAldo-keto ReductaseMolecular BiologyErythromycin BiosynthesisRedox Biology +17

Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis

Stephan J. Kakavas, Leonard Katz, Diane L. Stassi

Journal of Bacteriology

EngineeringBacteriologyMolecular BiologyNiddamycin ProductionNiddamycin Biosynthetic Pathway +14

Facilitation of Plasmid Transfer in <i>Streptococcus pneumoniae</i> by Chromosomal Homology

Paloma López, Manuel Espinosa, Diane L. Stassi, +1

Journal of Bacteriology

Chromosomal HomologyGeneticsBacteriologyMolecular BiologyBacterial Pathogens +14

Effect of strong promoters on the cloning in Escherichia coli of DNA fragments from Streptococcus pneumoniae

Diane L. Stassi, Sanford A. Lacks

Gene

Streptococcus PneumoniaeStrong PromotersNatural SciencesBacteriologyDna Replication +6

A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain

Xiaoan Ruan, Diane L. Stassi, S.A. Lax, +1

Gene

Microbial SystematicsMolecular BiologyRapamycin-producing StrainMicrobiologyMedicine +2

The loading domain of the erythromycin polyketide synthase is not essential for erythromycin biosynthesis in Saccharopolyspora erythraea

Ana Pereda, R G Summers, Diane L. Stassi, +2

Microbiology

Bioorganic ChemistryEngineeringMolecular BiologyErythromycin BiosynthesisEnzymatic Modification +16

Nucleotide sequence of DNA controlling expression of genes for maltosaccharide utilization in Streptococcus pneumoniae

Diane L. Stassi, John J. Dunn, Sanford A. Lacks

Gene

Streptococcus PneumoniaeMedicineBacteriologyMolecular BiologyMaltosaccharide Utilization +6