Sanjay C. Panchal

Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer

Emily J. Faivre, Keith F. McDaniel, Daniel H. Albert et al. · Nature · 2020 · 389 citations

Bd2 Bromodomain, Medicine, Natural Sciences +9

Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain

Takanori Otomo, Diana R. Tomchick, Chinatsu Otomo et al. · Nature · 2005 · 366 citations

Protein Assembly, Natural Sciences, Actin Filament Nucleation +11

Mechanistic Dissection of PARP1 Trapping and the Impact on <i>In Vivo</i> Tolerability and Efficacy of PARP Inhibitors

Todd A. Hopkins, Yan Shi, Luis E. Rodrı́guez et al. · Molecular Cancer Research · 2015 · 257 citations

PARP1 Trapping by PARP Inhibitors Drives Cytotoxicity in Both Cancer Cells and Healthy Bone Marrow

Todd A. Hopkins, William B. Ainsworth, Paul A. Ellis et al. · Molecular Cancer Research · 2018 · 250 citations

The EED protein–protein interaction inhibitor A-395 inactivates the PRC2 complex

Yupeng He, Sujatha Selvaraju, Michael L. Curtin et al. · Nature Chemical Biology · 2017 · 229 citations · Full text

Protein Function, Signal Transduction, Molecular Regulation +7