Simon Brocklehurst

An Integrated Characterization of Serological, Pathological, and Functional Events in Doxorubicin-Induced Cardiotoxicity

Laura Cove-Smith, Neil Woodhouse, Adam Hargreaves et al. · Toxicological Sciences · 2014 · 57 citations

Cardiac Muscle, Heart Failure, Pathology +23

Aortic Binding of AZD5248: Mechanistic Insight and Reactivity Assays To Support Lead Optimzation

Ryan A. Bragg, Simon Brocklehurst, Frida Gustafsson et al. · Chemical Research in Toxicology · 2015 · 27 citations

Lead Identification, Pharmacotherapy, Inhibitor Azd5248 +18

Islets of Langerhans from prohormone convertase‐2 knockout mice show α‐cell hyperplasia and tumorigenesis with elevated α‐cell neogenesis

Huw B. Jones, Jaimini Reens, Simon Brocklehurst et al. · International Journal of Experimental Pathology · 2014 · 15 citations · Full text

A pilot evaluation of the use of tissue microarrays for quantitation of target distribution in drug discovery pathology

Jennifer S. McKay, Alison Bigley, Alex Bell et al. · Experimental and Toxicologic Pathology · 2005 · 12 citations

Target Distribution, Drug Target, Hit Identification +11