S. Wayne Mascarella

Structure of the human κ-opioid receptor in complex with JDTic

Huixian Wu, Daniel Wacker, Mauro Mileni et al. · Nature · 2012 · 871 citations · Full text

Medicine, Molecular Biology, Pharmacology +12

Synthesis and Biological Evaluation of Bupropion Analogues as Potential Pharmacotherapies for Smoking Cessation

F. Ivy Carroll, Bruce E. Blough, S. Wayne Mascarella et al. · Journal of Medicinal Chemistry · 2010 · 118 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Identification of the First <i>trans</i>-(3<i>R</i>,4<i>R</i>)- Dimethyl-4-(3-hydroxyphenyl)piperidine Derivative To Possess Highly Potent and Selective Opioid κ Receptor Antagonist Activity

James B. Thomas, Robert N. Atkinson, Richard B. Rothman et al. · Journal of Medicinal Chemistry · 2001 · 106 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Synthesis, Ligand Binding, and QSAR (CoMFA and Classical) Study of 3.beta.-(3'-Substituted phenyl)-, 3.beta.-(4'-Substituted phenyl)-, and 3.beta.-(3',4'-Disubstituted phenyl)tropane-2.beta.-carboxylic Acid Methyl Esters

F. Ivy Carroll, S. Wayne Mascarella, Michael A. Kuzemko et al. · Journal of Medicinal Chemistry · 1994 · 104 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6

Structure−Activity Analysis of Anandamide Analogs:  Relationship to a Cannabinoid Pharmacophore

Brian F. Thomas, Irma B. Adams, S. Wayne Mascarella et al. · Journal of Medicinal Chemistry · 1996 · 88 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11