Dexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a/HO-1 signaling pathway

Jia Shi, Tianxi Yu, Kai Song, +10

Redox Biology

NAD⁺ ameliorates endotoxin‐induced acute kidney injury in a sirtuin1–dependent manner via GSK‐3β/Nrf2 signalling pathway

Simeng He, Qiaoying Gao, Xiaoyang Wu, +7

Journal of Cellular and Molecular Medicine

Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury by modulating macrophage polarization via the SIRT1/NF-κB pathway

Simeng He, Xianhong Jiang, Jing Yang, +8

Pharmaceutical Biology

RNA Helicase DDX24 Stabilizes LAMB1 to Promote Hepatocellular Carcinoma Progression

Tianze Liu, Hairun Gan, Simeng He, +21

Cancer Research

ALDH2 attenuates myocardial pyroptosis through breaking down Mitochondrion-NLRP3 inflammasome pathway in septic shock

Ying Zhang, Ying Lv, Qingju Zhang, +15

Frontiers in Pharmacology

Heart FailureLipid PeroxidationApoptosisImmunologyCell Death +19

Neutrophil ALDH2 is a new therapeutic target for the effective treatment of sepsis-induced ARDS

Changchang Xu, Lin Zhang, Shaoyu Xu, +16

Cellular and Molecular Immunology

Acute Lung InjuryInflammationAnti-inflammatoryLung InflammationGranulocyte +8

5-Methoxytryptophan ameliorates endotoxin-induced acute lung injury in vivo and in vitro by inhibiting NLRP3 inflammasome-mediated pyroptosis through the Nrf2/HO-1 signaling pathway

Yang Ma, Zhixue Wang, Xiaoyang Wu, +8

Inflammation Research

Acute Lung InjuryInflammationNlrp3 Inflammasome-mediated PyroptosisAnti-inflammatoryInflammatory Lung Disease +13

Ropivacaine inhibits wound healing by suppressing the proliferation and migration of keratinocytes via the PI3K/AKT/mTOR Pathway

Xiaoyang Wu, Quanyu Sun, Simeng He, +5

BMC Anesthesiology

Heme oxygenase-1 protects against endotoxin-induced acute lung injury depends on NAD+-mediated mitonuclear communication through PGC1α/PPARγ signaling pathway

Simeng He, Jia Shi, Wenming Liu, +8

Inflammation Research

Hydromorphone Protects against CO₂ Pneumoperitoneum‐Induced Lung Injury via Heme Oxygenase‐1‐Regulated Mitochondrial Dynamics

Jia Shi, Shihan Du, Jianbo Yu, +7

Oxidative Medicine and Cellular Longevity