Copsin, a Novel Peptide-based Fungal Antibiotic Interfering with the Peptidoglycan Synthesis

Andreas Essig, Daniela Hofmann, Daniela Münch, +7

Journal of Biological Chemistry

Identification and in vitro Analysis of the GatD/MurT Enzyme-Complex Catalyzing Lipid II Amidation in Staphylococcus aureus

Daniela Münch, Terry Roemer, Sang Ho Lee, +3

PLoS Pathogens

Proteomic Response of Bacillus subtilis to Lantibiotics Reflects Differences in Interaction with the Cytoplasmic Membrane

Michaela Wenzel, Bastian Kohl, Daniela Münch, +6

Antimicrobial Agents and Chemotherapy

Bacillus SubtilisProteinlipid InteractionProkaryotic SystemLipid IiBiochemistry +13

The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions

Daniela Münch, Anna Müller, Tanja Schneider, +8

Journal of Biological Chemistry

Characterization of co-translationally formed nanodisc complexes with small multidrug transporters, proteorhodopsin and with the E. coli MraY translocase

Christian Roos, Michael Zocher, Daniel J. Müller, +10

Biochimica et Biophysica Acta (BBA) - Biomembranes

BiochemistrySmall Multidrug TransportersNanodiscProtein NanoparticlesBiomolecular Engineering +1

Lipid Requirements for the Enzymatic Activity of MraY Translocases and in Vitro Reconstitution of the Lipid II Synthesis Pathway

Erik Henrich, Yi Ma, Ina Engels, +6

Journal of Biological Chemistry

Preparative Scale Cell-free Production and Quality Optimization of MraY Homologues in Different Expression Modes

Yi Ma, Daniela Münch, Tanja Schneider, +7

Journal of Biological Chemistry

Mray HomologuesEngineeringEscherichia ColiCell CultureProtein Synthesis +16

Structural Variations of the Cell Wall Precursor Lipid II and Their Influence on Binding and Activity of the Lipoglycopeptide Antibiotic Oritavancin

Daniela Münch, Ina Engels, Anna Müller, +7

Antimicrobial Agents and Chemotherapy

Structural VariationsProteinlipid InteractionAntimicrobial ChemotherapyLipid Ii MoleculeLipid Ii Stem +15

AmiA is a penicillin target enzyme with dual activity in the intracellular pathogen Chlamydia pneumoniae

Anna Klöckner, Christian Otten, Adeline Derouaux, +7

Nature Communications

The Nonantibiotic Small Molecule Cyslabdan Enhances the Potency of β-Lactams against MRSA by Inhibiting Pentaglycine Interpeptide Bridge Synthesis

Nobuhiro Koyama, Yuriko Tokura, Daniela Münch, +5

PLoS ONE