Rosemary A. Melarange

Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators

Simon E. Ward, Mark H Harries, Laura Aldegheri et al. · Journal of Medicinal Chemistry · 2010 · 65 citations · Full text

Proteinlipid Interaction, Ampar Positive Modulators, High Throughput +20

Evaluation of the mGlu8 receptor as a putative therapeutic target in schizophrenia

Melanie J. Robbins, Kathryn R. Starr, Andy Honey et al. · Brain Research · 2007 · 60 citations

Psychiatry, Psychotic Disorder, Medicine +10

Discovery of<i>N</i>-[(2<i>S</i>)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1<i>H</i>-inden-2-yl]-2-propanesulfonamide, a Novel Clinical AMPA Receptor Positive Modulator

Simon E. Ward, Mark H Harries, Laura Aldegheri et al. · Journal of Medicinal Chemistry · 2010 · 47 citations · Full text

.beta.1-Selective adrenoceptor antagonists. 3. 4-Azolyl linked phenoxypropanolamines

Peter J. Machin, David N. Hurst, Rachel M. Bradshaw et al. · Journal of Medicinal Chemistry · 1984 · 28 citations

.beta.1-Selective adrenoceptor antagonists. 2. 4-Ether-linked phenoxypropanolamines

Peter J. Machin, David N. Hurst, Rachel M. Bradshaw et al. · Journal of Medicinal Chemistry · 1983 · 19 citations