One-Dimensional Sliding of p53 Along DNA Is Accelerated in the Presence of Ca2+ or Mg2+ at Millimolar Concentrations

Agato Murata, Yuji Ito, Risa Kashima, +8

Journal of Molecular Biology

ChromatinGenome InstabilityNatural SciencesMillimolar ConcentrationsDna Replication +6

DNA Garden: A Simple Method for Producing Arrays of Stretchable DNA for Single-Molecule Fluorescence Imaging of DNA-Binding Proteins

Chihiro Igarashi, Agato Murata, Yuji Itoh, +3

Bulletin of the Chemical Society of Japan

Dna NanotechnologySingle Molecule BiophysicsFlow ControlNatural SciencesMolecular Biology +12

Activation of p53 Facilitates the Target Search in DNA by Enhancing the Target Recognition Probability

Yuji Itoh, Agato Murata, Seiji Sakamoto, +4

Journal of Molecular Biology

ChromatinP53 FacilitatesNucleic Acid BiomarkersNatural SciencesMolecular Biology +7

Characterization of facilitated diffusion of tumor suppressor p53 along DNA using single-molecule fluorescence imaging

Kiyoto Kamagata, Agato Murata, Yuji Itoh, +1

Journal of Photochemistry and Photobiology C Photochemistry Reviews

EngineeringOncologic ImagingFacilitated DiffusionNovel Imaging MethodTumor Suppressor P53 +11

The Disordered Linker in p53 Participates in Nonspecific Binding to and One-Dimensional Sliding along DNA Revealed by Single-Molecule Fluorescence Measurements

Dwiky Rendra Graha Subekti, Agato Murata, Yuji Itoh, +5

Biochemistry

Molecular BiologyOne-dimensional SlidingSingle Molecule BiophysicsP53 ParticipatesSingle Molecule +14

Intrinsically disordered domain of tumor suppressor p53 facilitates target search by ultrafast transfer between different DNA strands

Yuji Itoh, Agato Murata, Satoshi Takahashi, +1

Nucleic Acids Research

Molecular BiologyMolecular ResearchNucleic Acid BiomarkersTumor BiologySingle-molecule Fluorescence Measurements +18

One-Dimensional Search Dynamics of Tumor Suppressor p53 Regulated by a Disordered C-Terminal Domain

Agato Murata, Yuji Itoh, Eriko Mano, +5

Biophysical Journal

Tumor BiologyDisordered C-terminal DomainMedicineTumor Suppressor P53Computational Biology +7

Rational design using sequence information only produces a peptide that binds to the intrinsically disordered region of p53

Kiyoto Kamagata, Eriko Mano, Yuji Itoh, +6

Scientific Reports

Protein AssemblyStructural BioinformaticsMolecular BiologyPeptide ScienceBiological Computing +23

Transient binding and jumping dynamics of p53 along DNA revealed by sub-millisecond resolved single-molecule fluorescence tracking

Dwiky Rendra Graha Subekti, Agato Murata, Yuji Itoh, +2

Scientific Reports