Kristina M. DiFranco

Leukotoxin (Leukothera®) Targets Active Leukocyte Function Antigen-1 (LFA-1) Protein and Triggers a Lysosomal Mediated Cell Death Pathway

Kristina M. DiFranco, Anukriti Gupta, Lindsey E. Galusha et al. · Journal of Biological Chemistry · 2012 · 55 citations · Full text

Life Sciences, Immunology, Pharmacology +16

Potent in vitro and in vivo antifungal activity of a small molecule host defense peptide mimic through a membrane-active mechanism

Lorenzo P. Menzel, Hossain Mobaswar Chowdhury, Jorge A. Masso-Silva et al. · Scientific Reports · 2017 · 42 citations · Full text

Life Sciences, Microbiology, Pharmacology +17

LFA-1-targeting Leukotoxin (LtxA; Leukothera®) causes lymphoma tumor regression in a humanized mouse model and requires caspase-8 and Fas to kill malignant lymphocytes

Kristina M. DiFranco, Nadine Johnson-Farley, Joseph R. Bertino et al. · Leukemia Research · 2015 · 23 citations · Full text

Life Sciences, Immunology, Oncology +12

Induction of CFTR gene expression by 1,25(OH)2 vitamin D3, 25OH vitamin D3, and vitamin D3 in cultured human airway epithelial cells and in mouse airways

Kristina M. DiFranco, Jennifer K. Mulligan, Aman S. Sumal et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2017 · 22 citations · Full text

Medicine, Genetics, Molecular Genetics +10

Leukotoxin kills rodent WBC by targeting leukocyte function associated antigen 1.

Kristina M. DiFranco, Rajesh H Kaswala, Chandni Patel et al. · PubMed · 2013 · 13 citations · Full text

Medicine, Hematology, Immunology +10