Gemma Austin

The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia

Athina Giannoudis, Lihui Wang, Andrea Jorgensen et al. · Blood · 2012 · 70 citations · Full text

Medicine, Genetics, Molecular Genetics +7

Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial

Chris Parker, Noel W. Clarke, Adrian Cook et al. · The Lancet · 2024 · 49 citations · Full text

Medicine, Oncology, Surgery +15

Peroxisome proliferator–activated receptor activation increases imatinib uptake and killing of chronic myeloid leukemia cells

Lihui Wang, Athina Giannoudis, Gemma Austin et al. · Experimental Hematology · 2012 · 19 citations · Full text

Medicine, Cell Biology, Pharmacology +7

Evidence that the pregnane <scp>X</scp> and retinoid receptors <scp>PXR</scp>,<scp> RAR</scp> and <scp>RXR</scp> may regulate transcription of the transporter <i>h<scp>OCT</scp>1</i> in chronic myeloid leukaemia cells

Gemma Austin, Alison Holcroft, Natasha Rinne et al. · European Journal Of Haematology · 2014 · 15 citations

Life Sciences, Molecular Biology, Oncology +17

Dual Glutathione-S-Transferase-θ1 and -μ1 Gene Deletions Determine Imatinib Failure in Chronic Myeloid Leukemia

Andrea Davies, Athina Giannoudis, J E Zhang et al. · Clinical Pharmacology & Therapeutics · 2014 · 14 citations

Life Sciences, Genetics, Molecular Genetics +10