Mark A. R. de Geus

Click‐to‐Release from <i>trans</i>‐Cyclooctenes: Mechanistic Insights and Expansion of Scope from Established Carbamate to Remarkable Ether Cleavage

Ron M. Versteegen, Wolter ten Hoeve, Raffaella Rossin et al. · Angewandte Chemie International Edition · 2018 · 125 citations

Pharmacy, Biochemistry, Chemistry +15

Chemical Control over T-Cell Activation <i>in Vivo</i> Using Deprotection of <i>trans</i>-Cyclooctene-Modified Epitopes

Anouk M. F. van der Gracht, Mark A. R. de Geus, Marcel Camps et al. · ACS Chemical Biology · 2018 · 47 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Fast and pH‐Independent Elimination of <i>trans</i>‐Cyclooctene by Using Aminoethyl‐Functionalized Tetrazines

Alexi J. C. Sarris, Thomas Hansen, Mark A. R. de Geus et al. · Chemistry - A European Journal · 2018 · 44 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +14

A Lysosome-Targeted Tetrazine for Organelle-Specific Click-to-Release Chemistry in Antigen Presenting Cells

Nina A. M. Ligthart, Mark A. R. de Geus, Merel A. T. van de Plassche et al. · Journal of the American Chemical Society · 2023 · 40 citations · Full text

Life Sciences, Biochemistry, Immunology +17

DFT‐Guided Discovery of Ethynyl‐Triazolyl‐Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling

Christian E. Stieger, Y.H. Park, Mark A. R. de Geus et al. · Angewandte Chemie International Edition · 2022 · 31 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +7