Pınar Obakan

Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells

Yunus Akkoç, Özge Berrak, Elif Damla Arısan et al. · Biomedicine & Pharmacotherapy · 2015 · 85 citations

Inflammation, Cell Autophagy, Mitophagy +12

CDK Inhibitors Induce Mitochondria-mediated Apoptosis Through the Activation of Polyamine Catabolic Pathway in LNCaP, DU145 and PC3 Prostate Cancer Cells

Pınar Obakan, Ajda Çoker Gürkan, Annarica Calcabrini et al. · Current Pharmaceutical Design · 2014 · 40 citations

Chemoprevention Strategy, Apoptosis, Cell Death +17

Activation of polyamine catabolic enzymes involved in diverse responses against epibrassinolide-induced apoptosis in LNCaP and DU145 prostate cancer cell lines

Pınar Obakan, Elif Damla Arısan, Annarica Calcabrini et al. · Amino Acids · 2013 · 30 citations

Biochemistry, Medicine, Natural Sciences +10

Inhibition of autophagy by 3-MA potentiates purvalanol-induced apoptosis in Bax deficient HCT 116 colon cancer cells

Ajda Çoker Gürkan, Elif Damla Arısan, Pınar Obakan et al. · Experimental Cell Research · 2014 · 27 citations

Cell Autophagy, Mitophagy, Colon Cancer Cells +8

Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells

Deniz Coşkun, Pınar Obakan, Elif Damla Arısan et al. · Experimental Cell Research · 2015 · 25 citations

Signaling Pathway, Chemoprevention Strategy, Colon Cancer Cells +11