Frequency of TERT promoter mutations in human cancers

João Vinagre, Ana Paula de Almeida, Helena Pópulo, +21

Nature Communications

Somatic VariantTert Promoter MutationsPathologyCancer GenomicsCancer Genetics +3

BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC

Paula Soares, Vítor Trovisco, Ana Sofia Rocha, +7

Oncogene

Genome InstabilityAlternative EventsCell DivisionBraf MutationsGenetics +6

Type and prevalence of BRAF mutations are closely associated with papillary thyroid carcinoma histotype and patients’ age but not with tumour aggressiveness

Vítor Trovisco, Paula Soares, Ana Preto, +8

Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin

MedicineBraf MutationsThyroid DiseasePathologyCancer Genetics +6

Distribution of p63, cytokeratins 5/6 and cytokeratin 14 in 51 normal and 400 neoplastic human tissue samples using TARP-4 multi-tumor tissue microarray

F�tima G�rtner, Fernando Schmitt, Ana Preto, +3

Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin

Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hürthle cell) tumours of the thyroid

Valdemar Máximo, Tiago O. Botelho, João Capela, +9

British Journal of Cancer

Dual Function GeneSomatic VariantMitochondrial BiogenesisMitochondrial FunctionThyroid Tumours +12

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression

Carla Oliveíra, Sérgia Velho, Cátia Moutinho, +10

Oncogene

OncologySomatic VariantOncogenic AgentMedicineColorectal Cancer +7

Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells

Cristina P. R. Xavier, Cristóvão F. Lima, Ana Preto, +3

Cancer Letters

MedicineApoptosisPharmacologyColorectal CancerCell Death +7

Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release

Carolina Marques, Catarina S. Oliveira, Sara Alves, +4

Cell Death and Disease

Cathepsin D ReleaseCatd InhibitorsApoptosisPathologyCell Death +18

p63 Expression in Solid Cell Nests of the Thyroid: Further Evidence for a Stem Cell Origin

Jorge S. Reis‐Filho, Ana Preto, Paula Soares, +3

Modern Pathology

Solid Cell NestsDevelopmental BiologyTissue DevelopmentCell DivisionMedicine +6

Molecular and Genotypic Characterization of Human Thyroid Follicular Cell Carcinoma–Derived Cell Lines

Ana Margarida Meireles, Ana Preto, Ana Sofia Rocha, +12

Thyroid