Federico La Regina

Impaired adult neurogenesis is an early event in Alzheimer’s disease neurodegeneration, mediated by intracellular Aβ oligomers

Chiara Scopa, Francesco Marrocco, Valentina Latina et al. · Cell Death and Differentiation · 2019 · 139 citations · Full text

Increased cytoplasmic TDP-43 reduces global protein synthesis by interacting with RACK1 on polyribosomes

Arianna Russo, Raffaella Scardigli, Federico La Regina et al. · Human Molecular Genetics · 2017 · 101 citations · Full text

Protein Assembly, Molecular Biology, Protein Synthesis +16

ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice

Cecilia Tiveron, Luisa Fasulo, Simona Capsoni et al. · Cell Death and Differentiation · 2013 · 73 citations · Full text

Memory Deficits, Knockout Mouse, Neurodegenerative Diseases +10

Sox2 is required for embryonic development of the ventral telencephalon through the activation of the ventral determinants Nkx2.1 and Shh

Rebecca Favaro, Leonardo Beccari, Jessica Bertolini et al. · Development · 2013 · 57 citations

Brain Development, Sox2 Transcription Factor, Cerebral Organoid +20

Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer’s Disease

Valentina Latina, Giacomo Giacovazzo, Federica Cordella et al. · Acta Neuropathologica Communications · 2021 · 38 citations · Full text