Samantha Gildenhuys

Benzofuran-selenadiazole hybrids as novel α-glucosidase and cyclooxygenase-2 inhibitors with antioxidant and cytotoxic properties

Temitope O. Olomola, Malose J. Mphahlele, Samantha Gildenhuys · Bioorganic Chemistry · 2020 · 34 citations

Medicinal Chemistry, Biochemistry, Medicine +8

Synthesis, α-glucosidase inhibition and antioxidant activity of the 7-carbo–substituted 5-bromo-3-methylindazoles

Malose J. Mphahlele, Nontokozo M. Magwaza, Samantha Gildenhuys et al. · Bioorganic Chemistry · 2020 · 32 citations

Medicinal Chemistry, Food Bioactive Compound, Biochemistry +4

Synthesis of furocoumarin–stilbene hybrids as potential multifunctional drugs against multiple biochemical targets associated with Alzheimer’s disease

Emmanuel N. Agbo, Samantha Gildenhuys, Yee Siew Choong et al. · Bioorganic Chemistry · 2020 · 30 citations

Biochemistry, Medicine, Bioconjugation +6

Arginine 15 stabilizes an SNAr reaction transition state and the binding of anionic ligands at the active site of human glutathione transferase A1-1

Samantha Gildenhuys, Marina A. Dobreva, Nichole Kinsley et al. · Biophysical Chemistry · 2009 · 23 citations

Protein Chemistry, Signal Transduction, Protein Expression +6

Synthesis, In Vitro Evaluation and Molecular Docking of the 5-Acetyl-2-aryl-6-hydroxybenzo[b]furans against Multiple Targets Linked to Type 2 Diabetes

Malose J. Mphahlele, Yee Siew Choong, Marole M. Maluleka et al. · Biomolecules · 2020 · 23 citations · Full text

Combinatorial Chemistry, Modelled Complexes, Pharmaceutical Chemistry +17