Steven McFarlane

A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research

Suzannah J. Rihn, Andres Merits, Siddharth Bakshi et al. · PLoS Biology · 2021 · 237 citations · Full text

Engineering, Genetics, Immunology +19

A Viral Ubiquitin Ligase Has Substrate Preferential SUMO Targeted Ubiquitin Ligase Activity that Counteracts Intrinsic Antiviral Defence

Chris Boutell, Delphine Cuchet-Lourenço, Emilia A. H. Vanni et al. · PLoS Pathogens · 2011 · 180 citations · Full text

Protein Function, Molecular Virology, Intrinsic Antiviral Defence +13

Human Cytomegalovirus Protein pp71 Displaces the Chromatin-Associated Factor ATRX from Nuclear Domain 10 at Early Stages of Infection

Vera Lukashchuk, Steven McFarlane, Roger D. Everett et al. · Journal of Virology · 2008 · 129 citations · Full text

Viral Replication, Viral Pathogenesis, Immunology +18

Early Induction of Autophagy in Human Fibroblasts after Infection with Human Cytomegalovirus or Herpes Simplex Virus 1

Steven McFarlane, James Aitken, Jane S. Sutherland et al. · Journal of Virology · 2011 · 123 citations · Full text

Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection

Thamir A. Alandijany, Ashley P. E. Roberts, Kristen L. Conn et al. · PLoS Pathogens · 2018 · 102 citations · Full text

Viral Replication, Immunology, Molecular Biology +18