Ambient pollutants, particularly fine particulate matter (PM_2.5) and ozone (O₃), pose significant risks to both public health and economic development. In recent years, PM_2.5 concentration in China has decreased significantly, whereas that of O₃ has increased rapidly, leading to considerable health risks. In this study, a generalized additive model was employed to establish the relationship of PM_2.5 and O₃ exposure with non-accidental mortality across 17 districts and counties in Jilin Province, China, over 2015-2016. The health burden and economic losses attributable to PM_2.5 and O₃ were assessed using high-resolution satellite and population data. According to the results, per 10 µg/m³ increase in PM_2.5 and O₃ concentrations related to an overall relative risk (95% confidence interval) of 1.004 (1.001-1.007) and 1.009 (1.005-1.012), respectively. In general, the spatial distribution of mortality and economic losses was uneven. Throughout the study period, a total of 23,051.274 mortalities and 27,825.015 million Chinese Yuan (CNY) in economic losses were attributed to O₃ exposure, which considerably surpassing the 5,450.716 mortalities and 6,553,780 million CNY in economic losses attributed to PM_2.5 exposure. The O₃-related health risks and economic losses increased by 3.75% and 9.3% from 2015 to 2016, while those linked to PM_2.5 decreased by 23.33% and 18.7%. Sensitivity analysis results indicated that changes in pollutant concentrations were the major factors affecting mortality rather than baseline mortality and population.

#	Concept	H-Index	Publications	Citations
1	Public Health	6	6	147
2	Medicine	3	3	73
3	Engineering	2	2	141
4	Business	1	1	29
5	Allergy	1	1	30

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