The Cyclooxygenase-2 Inhibitor Celecoxib Induces Apoptosis by Blocking Akt Activation in Human Prostate Cancer Cells Independently of Bcl-2

A. Hsu, Tsui‐Ting Ching, Da-Sheng Wang, +3

Journal of Biological Chemistry

HSF-1 Regulators DDL-1/2 Link Insulin-like Signaling to Heat-Shock Responses and Modulation of Longevity

Wei‐Chung Chiang, Tsui‐Ting Ching, Hee Chul Lee, +2

Cell

Lifespan ExtensionMetabolic SyndromeInsulin SignalingSignal TransductionAging +10

Genome-wide Hypomethylation in Human Glioblastomas Associated with Specific Copy Number Alteration, Methylenetetrahydrofolate Reductase Allele Status, and Increased Proliferation

Benoît Cadieux, Tsui‐Ting Ching, Scott R. VandenBerg, +1

Cancer Research

Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3

Tsui‐Ting Ching, Alika K. Maunakea, Peter Jun, +9

Nature Genetics

Bac MicroarraysEpigenetic ChangeGeneticsDna MethylationEpigenomics +9

Distinct ligand binding sites in integrin α3β1 regulate matrix adhesion and cell–cell contact

Feng Zhang, Clifford Tom, Matthias C. Kugler, +4

The Journal of Cell Biology

Cell AdhesionMolecular BiologyIntegrin Alpha3beta1Cellular PhysiologySrc Kinase Inhibition +17

Phosphoinositide 3-Kinase Facilitates Antigen-stimulated Ca2+ Influx in RBL-2H3 Mast Cells via a Phosphatidylinositol 3,4,5-Trisphosphate-sensitive Ca2+Entry Mechanism

Tsui‐Ting Ching, Ao‐Lin Hsu, Amy J. Johnson, +1

Journal of Biological Chemistry

Enhanced Energy Metabolism Contributes to the Extended Life Span of Calorie-restricted Caenorhabditis elegans

Yiyuan Yuan, Chandra Sekhar Rao Kadiyala, Tsui‐Ting Ching, +12

Journal of Biological Chemistry

BiologyEnergy HomeostasisEnergy MetabolismLongevityBioenergetics +9

Novel Function of Phosphoinositide 3-Kinase in T Cell Ca2+ Signaling

Ao‐Lin Hsu, Tsui‐Ting Ching, Goutam Sen, +4

Journal of Biological Chemistry

Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity

Tsui‐Ting Ching, Wei‐Chung Chiang, Ching-Shih Chen, +1

Aging Cell

AgingCell DeathMetabolic RemodelingOxidative StressInflammation +15

Integrin‐linked kinase modulates longevity and thermotolerance in <i>C. elegans</i> through neuronal control of <scp>HSF</scp>‐1

Caroline Kumsta, Tsui‐Ting Ching, Mayuko Nishimura, +11

Aging Cell

Integrin-linked KinaseMolecular RegulationCytoskeletonCellular PhysiologySocial Sciences +20