Concepedia

Douglas W. DeSimone

DW

54

Publications

5.2K

Citations

36

H-Index

1980

Active since

Affiliations

University of Virginia(Current)

University of Virginia Health System

Massachusetts Institute of Technology

Laboratoire de Biologie du Développement

Center for Cancer Research

Douglas W. DeSimone is an author at University of Virginia specializing in medicine, cell biology, and developmental biology.

Top concepts

MedicineCell BiologyDevelopmental BiologyMorphogenesisCell PhysiologyCell AdhesionMatrix BiologyEmbryologyBiologyCell Signaling

Publications per year

1980–2022

54

Publications

54

Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin

John W. Tamkun, Douglas W. DeSimone, Deborah Fonda et al. · Cell · 1986 · 855 citations

Transmembrane Linkage, Natural Sciences, Cell Adhesion +11

A Mechanoresponsive Cadherin-Keratin Complex Directs Polarized Protrusive Behavior and Collective Cell Migration

Gregory F. Weber, Maureen A. Bjerke, Douglas W. DeSimone · Developmental Cell · 2011 · 366 citations · Full text

Collective Cell Migration, Developmental Biology, Medicine +9

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels

Nidhi Batra, Sirisha Burra, Arlene J. Siller-Jackson et al. · Proceedings of the National Academy of Sciences · 2012 · 228 citations · Full text

Engineering, Molecular Biology, Mechanotransduction +22

Integrin-ECM Interactions Regulate Cadherin-Dependent Cell Adhesion and Are Required for Convergent Extension in Xenopus

Mungo Marsden, Douglas W. DeSimone · Current Biology · 2003 · 208 citations · Full text

Developmental Biology, Signal Transduction, Convergent Extension +11

Cadherin Adhesion, Tissue Tension, and Noncanonical Wnt Signaling Regulate Fibronectin Matrix Organization

Bette J. Dzamba, Károly Jakab, Mungo Marsden et al. · Developmental Cell · 2009 · 189 citations · Full text

Mechanobiology, Signal Transduction, Engineering +12

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