Prasanna K. Vaddi

EGCG Inhibits Tumor Growth in Melanoma by Targeting JAK-STAT Signaling and Its Downstream PD-L1/PD-L2-PD1 Axis in Tumors and Enhancing Cytotoxic T-Cell Responses

Dinoop Ravindran Menon, Yang Li, Takeshi Yamauchi et al. · Pharmaceuticals · 2021 · 89 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Elimination of SOX2/OCT4-Associated Prostate Cancer Stem Cells Blocks Tumor Development and Enhances Therapeutic Response

Prasanna K. Vaddi, Mark A. Stamnes, Huojun Cao et al. · Cancers · 2019 · 51 citations · Full text

Medicine, Cell Biology, Oncology +17

Inflammasome Sensor NLRP1 Confers Acquired Drug Resistance to Temozolomide in Human Melanoma

Zili Zhai, Jenny Mae Samson, Takeshi Yamauchi et al. · Cancers · 2020 · 28 citations · Full text

Life Sciences, Cancer Biology, Oncology +14

CTLA4 mRNA is downregulated by miR-155 in regulatory T cells, and reduced blood CTLA4 levels are associated with poor prognosis in metastatic melanoma patients

Prasanna K. Vaddi, Douglas G. Osborne, Andrew Nicklawsky et al. · Frontiers in Immunology · 2023 · 22 citations · Full text

Life Sciences, Immunology, Oncology +17

Computational Modeling of NLRP3 Identifies Enhanced ATP Binding and Multimerization in Cryopyrin-Associated Periodic Syndromes

Jenny Mae Samson, Dinoop Ravindran Menon, Prasanna K. Vaddi et al. · Frontiers in Immunology · 2020 · 16 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +17