Alexander L. Button

Combining generative artificial intelligence and on-chip synthesis for de novo drug design

Francesca Grisoni, Berend J. H. Huisman, Alexander L. Button et al. · Science Advances · 2021 · 153 citations · Full text

Automated de novo molecular design by hybrid machine intelligence and rule-driven chemical synthesis

Alexander L. Button, Daniel Merk, Jan A. Hiss et al. · Nature Machine Intelligence · 2019 · 103 citations · Full text

Engineering, Directed Evolution, Computational Biology +11

Hybrid Network Model for “Deep Learning” of Chemical Data: Application to Antimicrobial Peptides

Petra Schneider, Alex T. Müller, Gisela Gabernet et al. · Molecular Informatics · 2016 · 49 citations

Genome-wide Association Studies of Retinal Vessel Tortuosity Identify Numerous Novel Loci Revealing Genes and Pathways Associated With Ocular and Cardiometabolic Diseases

Mattia Tomasoni, Michael J. Beyeler, Sofía Ortín Vela et al. · Ophthalmology Science · 2023 · 35 citations · Full text

Genome-wide Association Study, Cardiometabolic Diseases, Genetics +8

Combining Generative Artificial Intelligence and On-Chip Synthesis for De Novo Drug Design

Francesca Grisoni, Berend Huisman, Alexander L. Button et al. · 2020 · 24 citations · Full text

Artificial Intelligence, Lead Compounds, Drug Target +19