Lifen Gao

Increased expression of programmed cell death protein 1 on NK cells inhibits NK-cell-mediated anti-tumor function and indicates poor prognosis in digestive cancers

Yuan Liu, Yufeng Cheng, Yong Xu et al. · Oncogene · 2017 · 366 citations · Full text

Tim-3 fosters HCC development by enhancing TGF-β-mediated alternative activation of macrophages

Wenjiang Yan, Xiao Liu, Hongxin Ma et al. · Gut · 2015 · 305 citations

T cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates natural killer cell suppression in chronic hepatitis B

Ying Ju, Nan Hou, Jing Meng et al. · Journal of Hepatology · 2010 · 220 citations

Mucin-domain-containing Molecule-3, Autoimmune Disease, T-regulatory Cell +10

Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-κB/TNF-α pathway

Huimin Yang, Tingting Xie, Dengren Li et al. · Molecular Metabolism · 2019 · 181 citations · Full text

Tim-3 Hampers Tumor Surveillance of Liver-Resident and Conventional NK Cells by Disrupting PI3K Signaling

Siyu Tan, Yong Xu, Zehua Wang et al. · Cancer Research · 2019 · 139 citations

Tumor Biology, Cancer Immunosurveillance, Hepatocellular Carcinoma +13