Zhengqiang Zou

FFPM, a PDE4 inhibitor, reverses learning and memory deficits in APP/PS1 transgenic mice via cAMP/PKA/CREB signaling and anti-inflammatory effects

Haibiao Guo, Yufang Cheng, Canmao Wang et al. · Neuropharmacology · 2017 · 128 citations

Memory Deficits, Signal Transduction, Medicine +10

Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-κB Inhibition

Zhengqiang Zou, Jiajia Chen, Hong-Fang Feng et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 56 citations

Roflumilast reverses polymicrobial sepsis-induced liver damage by inhibiting inflammation in mice

Hong-Fang Feng, Jiajia Chen, Haitao Wang et al. · Laboratory Investigation · 2017 · 45 citations · Full text

Inflammation, Anti-inflammatory, Hepatology +13

Discovery of <i>N</i>-Alkyl Catecholamides as Selective Phosphodiesterase-4 Inhibitors with Anti-neuroinflammation Potential Exhibiting Antidepressant-like Effects at Non-emetic Doses

Zhong‐Zhen Zhou, Yufang Cheng, Zhengqiang Zou et al. · ACS Chemical Neuroscience · 2016 · 35 citations

The phosphodiesterase-4 inhibitor, FCPR16, attenuates ischemia-reperfusion injury in rats subjected to middle cerebral artery occlusion and reperfusion

Jiajia Chen, Hui Yu, Jiahong Zhong et al. · Brain Research Bulletin · 2017 · 35 citations

Cerebrovascular Disease, Cerebral Vascular Regulation, Thrombosis +16