The Orally Available Spleen Tyrosine Kinase Inhibitor 2-[7-(3,4-Dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide Dihydrochloride (BAY 61-3606) Blocks Antigen-Induced Airway Inflammation in Rodents

Noriyuki Yamamoto, Keisuke Takeshita, Michitaka Shichijo, +8

Journal of Pharmacology and Experimental Therapeutics

A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders

Aimo Kannt, Sridharan Rajagopal, Sanjay Venkatachalapathi Kadnur, +26

Scientific Reports

Catalytic use of tin(II) reagents in organic synthesis

Nobuharu Iwasawa, Takeshi Yura, Teruaki Mukaiyama

Tetrahedron

Catalytic SynthesisOrganometallic CatalysisCatalysisChemistryCatalytic Use

Asymmetric Sulfenylation of Tin(II) Enolates of Ketones and 3-Acyl-2-oxazolidones. Application to the Synthesis of Optically Active Epoxides

Takeshi Yura, Nobuharu Iwasawa, Richard S. J. Clark, +1

Chemistry Letters

Optically Active EpoxidesChemical EngineeringEngineeringHeterocyclicOrganic Chemistry +11

Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase

Sven Ruf, Mahanandeesha S. Hallur, Nisha K. Anchan, +25

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryMedicineNatural SciencesNicotineMechanism Of Action +6

The Catalytic Asymmetric Michael Reaction of Tin(II) Enethiolates

Takeshi Yura, Nobuharu Iwasawa, Koichi Narasaka, +1

Chemistry Letters

Chemical EngineeringEngineeringCatalytic AmountsOrganic ChemistryStannous Triflate +7

A novel Syk kinase-selective inhibitor blocks antigen presentation of immune complexes in dendritic cells

Kosuke Nakashima, Toshio Kokubo, Michitaka Shichijo, +3

European Journal of Pharmacology

AllergyAutoimmune DiseaseImmunologyTumor ImmunityAntigen Processing +9

2-[(2-Aminobenzyl)sulfinyl]-1-(2-pyridyl)-1,4,5,6-tetrahydrocyclopent[<i>d</i>]imidazoles as a Novel Class of Gastric H⁺/K⁺-ATPase Inhibitors

Masaki Yamada, Takeshi Yura, Masamichi Morimoto, +5

Journal of Medicinal Chemistry

Combinatorial ChemistryBioorganic ChemistryAcid DegradationHeterocycle ChemistryChemical Biology +14

The Enantioselective Michael Reaction of Tin(II) Enolates

Takeshi Yura, Nobuharu Iwasawa, Teruaki Mukaiyama

Chemistry Letters

EngineeringVarious αChiral Diamine LigandsOrganic ChemistryStereoselective Synthesis +6

Benzimidazole derivatives as novel nonpeptide luteinizing hormone-releasing hormone (LHRH) antagonists. Part 2: Benzimidazole-5-sulfonamides

Yingfu Li, Mikayo Kataoka, Miyuki Tatsuta, +7

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryPharmaceutical ScienceBiochemistryBenzimidazole DerivativesMedicine +8