Makoto Asada

E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition

Junji Matsui, Yuji Yamamoto, Yasuhiro Funahashi et al. · International Journal of Cancer · 2007 · 538 citations

Angiogenesis, Angiogenesis Inhibition, Tumor Growth +13

Multi-Kinase Inhibitor E7080 Suppresses Lymph Node and Lung Metastases of Human Mammary Breast Tumor MDA-MB-231 via Inhibition of Vascular Endothelial Growth Factor-Receptor (VEGF-R) 2 and VEGF-R3 Kinase

Junji Matsui, Yasuhiro Funahashi, Toshimitsu Uenaka et al. · Clinical Cancer Research · 2008 · 516 citations · Full text

Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage

Yuji Yamamoto, Junji Matsui, Tomohiro Matsushima et al. · Vascular Cell · 2014 · 478 citations · Full text

Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled trial

Faustino Torrico, Joaquím Gascón, Lourdes Ortiz et al. · The Lancet Infectious Diseases · 2018 · 292 citations · Full text

Pharmacology, Gastroenterology, Placebo-controlled Trial +2

Novel sulfonamides as potential, systemically active antitumor agents

Hiroshi Yoshino, Norihiro Ueda, Jun Niijima et al. · Journal of Medicinal Chemistry · 1992 · 233 citations

Chemoprevention Strategy, Altmetric Attention Score, Pharmacotherapy +20