Increased Brain Penetration and Potency of a Therapeutic Antibody Using a Monovalent Molecular Shuttle

Jens Niewoehner, Bernd Bohrmann, Ludovic Collin, +10

Neuron

Cell-based Drug DeliveryNanomedicineMedicineImmunologyBrain Penetration +7

A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies

Jan Olaf Stracke, Thomas Emrich, Petra Rueger, +11

mAbs

Improved Fcrn BindingPharmaceutical ScienceImmunocytochemical TechniqueMethionine OxidationPharmacotherapy +21

Bispecific digoxigenin-binding antibodies for targeted payload delivery

Silke Metz, Alexander K. Haas, Karin Daub, +12

Proceedings of the National Academy of Sciences

A Novel Glycoengineered Bispecific Antibody Format for Targeted Inhibition of Epidermal Growth Factor Receptor (EGFR) and Insulin-like Growth Factor Receptor Type I (IGF-1R) Demonstrating Unique Molecular Properties

Juergen Schanzer, Katharina Wartha, Rebecca Croasdale, +13

Journal of Biological Chemistry

Human GrowthTargeted InhibitionGlycobiologyImmunologyAntibody Screening +7

Characterization of a re‐engineered, mesothelin‐targeted<i>Pseudomonas</i>exotoxin fusion protein for lung cancer therapy

Frieder Bauss, Martin Lechmann, Ben‐Fillippo Krippendorff, +17

Molecular Oncology

Absence of preferential homologous H/L chain association in hybrid hybridomas

Wilma Lau, K Heije, Jacques Neefjes, +3

The Journal of Immunology

Development of tetravalent IgG1 dual targeting IGF-1R–EGFR antibodies with potent tumor inhibition

Rebecca Croasdale, Katharina Wartha, Juergen Schanzer, +20

Archives of Biochemistry and Biophysics

Igf-1r–egfr AntibodiesMedicineImmunologyTumor ImmunityTetravalent Igg1 +9

Targeted siRNA Delivery and mRNA Knockdown Mediated by Bispecific Digoxigenin-binding Antibodies

Britta Schneider, Michael Grote, Matthias John, +20

Molecular Therapy — Nucleic Acids

Cell-based Drug DeliveryBsab-sirna ComplexesImmunologyTumor ImmunitySirna Values +12

HB4 antibody recognizes a carbohydrate structure on lymphocyte surface proteins related to HB6, CDw75, and CD76 antigens

Wilma Lau, Jeroen Kuipers, Hans Voshol, +2

The Journal of Immunology