Tristan A. Reekie

Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists

Alexander Gillis, Arisbel B. Gondin, Andrea Kliewer et al. · Science Signaling · 2020 · 350 citations · Full text

Biased Agonism, Opioid Epidemic, Pain Medicine +23

Cubanes in Medicinal Chemistry

Tristan A. Reekie, Craig M. Williams, Louis M. Rendina et al. · Journal of Medicinal Chemistry · 2018 · 147 citations · Full text

Combinatorial Chemistry, Hydrocarbon System, Medicinal Chemistry +14

Challenges and Opportunities in Central Nervous System Drug Discovery

Jonathan J. Danon, Tristan A. Reekie, Michael Kassiou · Trends in Chemistry · 2019 · 81 citations · Full text

Drug Target, Medicine, Rational Drug Design +4

Body temperature and cardiac changes induced by peripherally administered oxytocin, vasopressin and the non‐peptide oxytocin receptor agonist <scp>WAY</scp> 267,464: a biotelemetry study in rats

Callum Hicks, Linnet Ramos, Tristan A. Reekie et al. · British Journal of Pharmacology · 2014 · 80 citations · Full text

In vivo assessment of neuroinflammation in progressive multiple sclerosis: a proof of concept study with [18F]DPA714 PET

Marloes Hagens, Sandeep S.V. Golla, Martijn T. Wijburg et al. · Journal of Neuroinflammation · 2018 · 79 citations · Full text