Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression.

Geoffrey M. Kapler, Cara M. Coburn, Stephen M. Beverley

Molecular and Cellular Biology

Parasitic DiseaseGeneticsMolecular BiologyEscherichia ColiMolecular Genetics +21

A Putative Cyclic Nucleotide–Gated Channel Is Required for Sensory Development and Function in C. elegans

Cara M. Coburn, Cornelia I. Bargmann

Neuron

Molecular NeuroscienceMolecular PhysiologySignal TransductionSensory NeuroscienceDevelopmental Biology +11

Double targeted gene replacement for creating null mutants.

Ângela K. Cruz, Cara M. Coburn, Stephen M. Beverley

Proceedings of the National Academy of Sciences

Double GeneEngineeringReverse GeneticsParasitic ProtozoaGenetics +13

Amino acid substitutions in the structured domains of histones H3 and H4 partially relieve the requirement of the yeast SWI/SNF complex for transcription.

Warren D. Kruger, Craig L. Peterson, Anita Sil, +4

Genes & Development

Histone ModificationsHo GeneEpigenetic ChangeGeneticsMolecular Biology +19

Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes.

Jonathan H. LeBowitz, Cara M. Coburn, Diane McMahon‐Pratt, +1

Proceedings of the National Academy of Sciences

EngineeringImmunologyGlycobiologyMolecular BiologyPathology +21

The Cyclic GMP-Dependent Protein Kinase EGL-4 Regulates Olfactory Adaptation in C. elegans

Noëlle D. L’Étoile, Cara M. Coburn, Jeffery Eastham, +3

Neuron

Signal TransductionMolecular NeuroscienceMolecular PhysiologyDevelopmental BiologySignaling Pathway +6

Stable Transfection of the Human Parasite <i>Leishmania major</i> Delineates a 30-Kilobase Region Sufficient for Extrachromosomal Replication and Expression

Geoffrey M. Kapler, Cara M. Coburn, Stephen M. Beverley

Molecular and Cellular Biology

Parasitic DiseaseGeneticsMolecular BiologyEscherichia ColiMolecular Genetics +21

A cyclic nucleotide-gated channel inhibits sensory axon outgrowth in larval and adult <i>Caenorhabditis elegans:</i> a distinct pathway for maintenance of sensory axon structure

Cara M. Coburn, Ikue Mori, Yasumi Ohshima, +1

Development

Synaptic TransmissionGeneticsNormal ChemotaxisNeurotransmissionCyclic Nucleotide-gated Channel +21

Stable DNA transfection of a wide range of trypanosomatids

Cara M. Coburn, Karen M. Otteman, Tessie McNeely, +2

Molecular and Biochemical Parasitology

Parasitic ProtozoaNatural SciencesAfrican TrypanosomiasisDna ReplicationMolecular Biology +2

Simultaneous transient expression assays of the trypanosomatid parasite Leishmania using β-galactosidase and β-glucuronidase as reporter enzymes

Jonathan H. LeBowitz, Cara M. Coburn, Stephen M. Beverley

Gene

Parasitic DiseaseBiochemistryParasitic ProtozoaNatural SciencesTrypanosomatid Parasite Leishmania +6