In Situ Regulation of Macrophage Polarization to Enhance Osseointegration Under Diabetic Conditions Using Injectable Silk/Sitagliptin Gel Scaffolds

Geng Xiang, Keyin Liu, Tianji Wang, +6

Advanced Science

Tissue EngineeringEngineeringImmunologyBiomaterials DesignBiofabrication +18

Promotion of osteointegration under diabetic conditions by tantalum coating-based surface modification on 3-dimensional printed porous titanium implants

Lin Wang, Xiaofan Hu, Xiangyu Ma, +6

Colloids and Surfaces B Biointerfaces

Materials ScienceTissue EngineeringEngineeringPorous Titanium ImplantsBioceramic +7

Angiogenesis impairment by the NADPH oxidase-triggered oxidative stress at the bone-implant interface: Critical mechanisms and therapeutic targets for implant failure under hyperglycemic conditions in diabetes

Xiaofan Hu, Lin Wang, Geng Xiang, +2

Acta Biomaterialia

Tissue EngineeringMetabolic SyndromeAngiogenesis ImpairmentPhysiologyDiabetes +11

The analgesic effects of triptolide in the bone cancer pain rats via inhibiting the upregulation of HDACs in spinal glial cells

Xiaofan Hu, Xiao‐Tao He, Kaixiang Zhou, +6

Journal of Neuroinflammation

Adiponectin improves the osteointegration of titanium implant under diabetic conditions by reversing mitochondrial dysfunction via the AMPK pathway in vivo and in vitro

Xiaofan Hu, Lin Wang, Yizhao Lu, +9

Acta Biomaterialia

MechanobiologyTissue EngineeringMetabolic SyndromeRegenerative MedicineAmpk Pathway +12

Suppression of histone deacetylases by SAHA relieves bone cancer pain in rats via inhibiting activation of glial cells in spinal dorsal horn and dorsal root ganglia

Xiao‐Tao He, Xiaofan Hu, Chao Zhu, +11

Journal of Neuroinflammation

The novel and potent anti-depressive action of triptolide and its influences on hippocampal neuroinflammation in a rat model of depression comorbidity of chronic pain

Xiaofan Hu, Yu‐Lin Dong, Xiaohang Jin, +5

Brain Behavior and Immunity

PsychiatryPain MedicineMedicineDepressionPsychopharmacology +12

Impairment of type H vessels by NOX2-mediated endothelial oxidative stress: critical mechanisms and therapeutic targets for bone fragility in streptozotocin-induced type 1 diabetic mice

Xiaofan Hu, Geng Xiang, Tianji Wang, +7

Theranostics

The impact of sitagliptin on macrophage polarity and angiogenesis in the osteointegration of titanium implants in type 2 diabetes

Geng Xiang, Xinyi Huang, Tianji Wang, +6

Biomedicine & Pharmacotherapy

Lactic acid of PLGA coating promotes angiogenesis on the interface between porous titanium and diabetic bone

Xiaofan Hu, Yafei Feng, Geng Xiang, +2

Journal of Materials Chemistry B