François D’Hooge

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Publications

Citations

1.1K

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Active since

2001

Affiliations

Spirogen (United Kingdom)(Current)

University of Bath

University of Birmingham

University College London

University of Oxford

François D’Hooge is an author at Spirogen (United Kingdom) specializing in antibody-drug conjugates, antibody-drug conjugate therapy, and cancer pharmacology.

ORCID

Publications per year

2001–2024

Publications

ADCT-402, a PBD dimer–containing antibody drug conjugate targeting CD19-expressing malignancies

Francesca Zammarchi, Simon Corbett, Lauren Adams et al. · Blood · 2018 · 181 citations · Full text

Pharmacy, Oncology, Pharmaceutics +13

Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody–Drug Conjugates Using Click Cycloaddition Chemistry

Michael Pete VanBrunt, Kurt Shanebeck, Zachary Caldwell et al. · Bioconjugate Chemistry · 2015 · 142 citations

Pharmacy, Medicinal Chemistry, Oncology +17

ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer–Containing Antibody–Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies

Michael Flynn, Francesca Zammarchi, Peter Tyrer et al. · Molecular Cancer Therapeutics · 2016 · 127 citations · Full text

Medicine, Oncology, Pharmacology +17

Dye displacement assay for saccharide detection with boronate hydrogels

M. J. Winson, Marta P. Pereira Morais, François D’Hooge et al. · Chemical Communications · 2008 · 86 citations

Engineering, Bioengineering, Biosensors +7

TR1801‐ADC: a highly potent cMet antibody–drug conjugate with high activity in patient‐derived xenograft models of solid tumors

Marco Gymnopoulos, Oscar Betancourt, Vincent Blot et al. · Molecular Oncology · 2019 · 67 citations · Full text

Medicine, Oncology, Pharmacology +17

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