Thomas M. D. Sheard

Three-Dimensional and Chemical Mapping of Intracellular Signaling Nanodomains in Health and Disease with Enhanced Expansion Microscopy

Thomas M. D. Sheard, Miriam E. Hurley, John Colyer et al. · ACS Nano · 2019 · 44 citations · Full text

Cardiac Muscle, Engineering, Microscopy +27

Three-dimensional visualization of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads

Thomas M. D. Sheard, Miriam E. Hurley, Andrew J. Smith et al. · Philosophical Transactions of the Royal Society B Biological Sciences · 2022 · 24 citations · Full text

Cardiac Muscle, Biophysical Modeling, Heart Failure +16

Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease

Miriam E. Hurley, Ed White, Thomas M. D. Sheard et al. · Open Biology · 2023 · 13 citations · Full text

A correlative super-resolution protocol to visualise structural underpinnings of fast second-messenger signalling in primary cell types

Miriam E. Hurley, Thomas M. D. Sheard, Ruth Norman et al. · Methods · 2020 · 12 citations

Correlative Super-resolution Protocol, Primary Cell Types, Molecular Physiology +14

Differential labelling of human sub-cellular compartments with fluorescent dye esters and expansion microscopy

Thomas M. D. Sheard, Tayla Shakespeare, Rajpinder S. Seehra et al. · Nanoscale · 2023 · 12 citations · Full text