Takatsugu Inoue

Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers

Manuela Molzan, Stefan Kasper, Lars Röglin et al. · ACS Chemical Biology · 2013 · 126 citations

Chemoprevention Strategy, Somatic Ras Mutations, Cancer Biology +18

A Structural Rationale for Selective Stabilization of Anti-tumor Interactions of 14-3-3 proteins by Cotylenin A

Christian Ottmann, Michael Weyand, Takeshi Sassa et al. · Journal of Molecular Biology · 2009 · 92 citations

Protein Function, Biochemistry, Natural Sciences +11

A Novel Fusicoccin Derivative Preferentially Targets Hypoxic Tumor Cells and Inhibits Tumor Growth in Xenografts

Koshi Kawakami, Miho Hattori, Takatsugu Inoue et al. · Anti-Cancer Agents in Medicinal Chemistry · 2012 · 35 citations

Semisynthesis and biological evaluation of a cotylenin A mimic derived from fusicoccin A

Takatsugu Inoue, Yusuke Higuchi, Toru Yoneyama et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 23 citations · Full text

Biosynthesis, Bioorganic Chemistry, Engineering +11

Structure–activity relationship studies on niphimycin, a guanidylpolyol macrolide antibiotic. Part 1: The role of the N-methyl-N″-alkylguanidinium moiety

Yoshinosuke Usuki, K. Matsumoto, Takatsugu Inoue et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 16 citations

Medicinal Chemistry, Antimicrobial Drug Discovery, Guanidylpolyol Macrolide +13