SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation

Zhiya Deng, Maomao Sun, Jie Wu, +9

Cell Death and Disease

Acute Lung InjuryInflammationMitophagySirt1-induced AutophagySignal Transduction +13

p53 Deacetylation Alleviates Sepsis-Induced Acute Kidney Injury by Promoting Autophagy

Maomao Sun, Jiaxin Li, Liangfeng Mao, +7

Frontiers in Immunology

MitophagyApoptosisImmunologyRenal InflammationCell Death +16

PDHA1 hyperacetylation-mediated lactate overproduction promotes sepsis-induced acute kidney injury via Fis1 lactylation

Sheng An, Yi Yao, Hongbin Hu, +11

Cell Death and Disease

Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation

Zhiya Deng, Man He, Hongbin Hu, +14

Autophagy

Renal PathologyImmunologyRenal InflammationCell DeathPathology +23

STING signaling sensing of DRP1-dependent mtDNA release in kupffer cells contributes to lipopolysaccharide-induced liver injury in mice

Qin Zhang, Jia‐Yi Wei, Zhuanhua Liu, +8

Redox Biology

Melatonin Attenuates Sepsis-Induced Small-Intestine Injury by Upregulating SIRT3-Mediated Oxidative-Stress Inhibition, Mitochondrial Protection, and Autophagy Induction

Siqi Xu, Lulan Li, Jie Wu, +6

Frontiers in Immunology

Polydatin protects against lipopolysaccharide-induced endothelial barrier disruption via SIRT3 activation

Jie Wu, Zhiya Deng, Maomao Sun, +11

Laboratory Investigation

InflammationCytokineSirt3 ActivationAnti-inflammatoryImmunology +6

Remimazolam reduces sepsis-associated acute liver injury by activation of peripheral benzodiazepine receptors and p38 inhibition of macrophages

Haihong Fang, Yidong Zhang, Jiancheng Wang, +7

International Immunopharmacology

InflammationPeripheral Benzodiazepine ReceptorsMedicineSepsisHepatotoxicity +4

Role of Src in Vascular Hyperpermeability Induced by Advanced Glycation End Products

Weijin Zhang, Qiulin Xu, Jie Wu, +6

Scientific Reports

Sirt1 Protects Endothelial Cells against LPS‐Induced Barrier Dysfunction

Weijin Zhang, Yaoyuan Zhang, Xiaohua Guo, +7

Oxidative Medicine and Cellular Longevity