Torsten Steinbrunn

The PI3K/Akt signaling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma

Manik Chatterjee, Mindaugas Andrulis, Thorsten Stühmer et al. · Haematologica · 2012 · 158 citations · Full text

Medicine, Cancer Biology, Molecular Medicine +13

Mutated RAS and constitutively activated Akt delineate distinct oncogenic pathways, which independently contribute to multiple myeloma cell survival

Torsten Steinbrunn, Thorsten Stühmer, Stefan Gattenlöhner et al. · Blood · 2010 · 84 citations

Medicine, Cancer Biology, Oncology +14

Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores angiogenic homeostasis and suppresses tumor progression

Antonio Giovanni Solimando, Matteo Da Vià, Patrizia Leone et al. · Haematologica · 2020 · 60 citations · Full text

Medicine, Cell Biology, Oncology +17

Multiple myeloma is affected by multiple and heterogeneous somatic mutations in adhesion- and receptor tyrosine kinase signaling molecules

Ellen Leich, Susann Weißbach, T. Grieb et al. · Blood Cancer Journal · 2013 · 59 citations · Full text

Medicine, Molecular Biology, Oncology +17

A GRP78-Directed Monoclonal Antibody Recaptures Response in Refractory Multiple Myeloma with Extramedullary Involvement

Leo Rasche, Emmanuelle Ménoret, Valentina Dubljevic et al. · Clinical Cancer Research · 2016 · 57 citations · Full text

Medicine, Immunology, Oncology +16