Sonja Sievers

Frequent promoter hypermethylation of Wnt pathway inhibitor genes in malignant astrocytic gliomas

Silke Götze, Marietta Wolter, Guido Reifenberger et al. · International Journal of Cancer · 2009 · 139 citations · Full text

Neuro-oncology, Aberrant Activation, Oncogenic Agent +11

Programming inactive RNA-binding small molecules into bioactive degraders

Yuquan Tong, Yeongju Lee, Xiaohui Liu et al. · Nature · 2023 · 132 citations · Full text

Chromopynones are pseudo natural product glucose uptake inhibitors targeting glucose transporters GLUT-1 and -3

George Karageorgis, Elena S. Reckzeh, Javier Ceballos et al. · Nature Chemistry · 2018 · 116 citations

Medicinal Chemistry, Biochemistry, Medicine +7

Phenyl Esters Are Potent Inhibitors of Caseinolytic Protease P and Reveal a Stereogenic Switch for Deoligomerization

Mathias W. Hackl, Markus Lakemeyer, Maria Dahmen et al. · Journal of the American Chemical Society · 2015 · 110 citations

Antibiotic Adjuvant, Enzymatic Modification, Pharmaceutical Chemistry +17

Natural product fragment combination to performance-diverse pseudo-natural products

Michael Grigalunas, Annina Burhop, Sarah Zinken et al. · Nature Communications · 2021 · 108 citations · Full text