Mathias W. Hackl

Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms

Philipp Le, Elena Kunold, Robert Macsics et al. · Nature Chemistry · 2019 · 135 citations · Full text

Antimicrobial Susceptibility, Drug-resistant Staphylococcus Aureus, Antibiotics +13

Phenyl Esters Are Potent Inhibitors of Caseinolytic Protease P and Reveal a Stereogenic Switch for Deoligomerization

Mathias W. Hackl, Markus Lakemeyer, Maria Dahmen et al. · Journal of the American Chemical Society · 2015 · 110 citations

Antibiotic Adjuvant, Enzymatic Modification, Pharmaceutical Chemistry +17

Towards synthetic cells using peptide-based reaction compartments

Kilian Vogele, Thomas Frank, Lukas Gasser et al. · Nature Communications · 2018 · 100 citations · Full text

Reversible Inhibitors Arrest ClpP in a Defined Conformational State that Can Be Revoked by ClpX Association

Axel Pahl, Markus Lakemeyer, M.-T. Vielberg et al. · Angewandte Chemie International Edition · 2015 · 44 citations

Design and synthesis of tailored human caseinolytic protease P inhibitors

Thomas F. Gronauer, Melanie M. Mandl, Markus Lakemeyer et al. · Chemical Communications · 2018 · 35 citations