David Mottola

Trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine: a highly potent selective dopamine D1 full agonist

William K. Brewster, David E. Nichols, Robert M. Riggs et al. · Journal of Medicinal Chemistry · 1990 · 169 citations · Full text

Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: Treprostinil is a potent DP1 and EP2 agonist

Brendan J.R. Whittle, Adam M. Silverstein, David Mottola et al. · Biochemical Pharmacology · 2012 · 162 citations · Full text

Immunology, Pulmonary Hypertension, Pharmacotherapy +16

Functional Selectivity of Dopamine Receptor Agonists. I. Selective Activation of Postsynaptic Dopamine D2 Receptors Linked to Adenylate Cyclase

David Mottola, Jason D. Kilts, Mechelle M. Lewis et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 122 citations · Full text

Dihydrexidine, a novel selective high potency full dopamine D-1 receptor agonist

Timothy W. Lovenberg, William K. Brewster, David Mottola et al. · European Journal of Pharmacology · 1989 · 105 citations

Molecular Pharmacology, Psychoactive Drug, Functional Selectivity +5

Conformational Analysis of D₁ Dopamine Receptor Agonists:  Pharmacophore Assessment and Receptor Mapping

David Mottola, Sergei Laiter, Val J. Watts et al. · Journal of Medicinal Chemistry · 1996 · 64 citations · Full text

Drug Target, Lowest Energy Conformation, Pharmacophore Assessment +17