Jason Jacintho

Discovery of a Series of Phosphonic Acid-Containing Thiazoles and Orally Bioavailable Diamide Prodrugs That Lower Glucose in Diabetic Animals Through Inhibition of Fructose-1,6-Bisphosphatase

Qun Dang, Yan Liu, Daniel K. Cashion et al. · Journal of Medicinal Chemistry · 2010 · 160 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis and Biological Evaluation of a Series of Liver-Selective Phosphonic Acid Thyroid Hormone Receptor Agonists and Their Prodrugs

Serge H. Boyer, Hongjian Jiang, Jason Jacintho et al. · Journal of Medicinal Chemistry · 2008 · 65 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

A Selective Novel Peroxisome Proliferator-Activated Receptor (PPAR)-α Antagonist Induces Apoptosis and Inhibits Proliferation of CLL Cells In Vitro and In Vivo

Davorka Messmer, Kymmy Lorrain, Karin J. Stebbins et al. · Molecular Medicine · 2015 · 42 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Identification of the first potent, selective and bioavailable PPARα antagonist

Yalda Bravo, Christopher Baccei, Alex Broadhead et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 11 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8