Karthik V. Karuppusamy

SMART-lipid nanoparticles enabled mRNA vaccine elicits cross-reactive humoral responses against the omicron sub-variants

Gokulnath Mahalingam, Hari Krishnareddy Rachamalla, Porkizhi Arjunan et al. · Molecular Therapy · 2024 · 20 citations · Full text

Pharmacy, Biomolecular Engineering, Immunology +17

The CCR5 Gene Edited CD34+CD90+ Hematopoietic Stem Cell Population Serves as an Optimal Graft Source for HIV Gene Therapy

Karthik V. Karuppusamy, John Paul Demosthenes, Vigneshwaran Venkatesan et al. · Frontiers in Immunology · 2022 · 18 citations · Full text

Medicine, Hematology, Immunology +10

Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies

Vigneshwaran Venkatesan, Abisha Crystal Christopher, Manuel Rhiel et al. · Molecular Therapy — Nucleic Acids · 2023 · 17 citations · Full text

Life Sciences, Genetics, Hematology +17

Preferential Expansion of Human CD34 ⁺ CD133 ⁺ CD90 ⁺ Hematopoietic Stem Cells Enhances Gene-Modified Cell Frequency for Gene Therapy

Abisha Crystal Christopher, Vigneshwaran Venkatesan, Karthik V. Karuppusamy et al. · Human Gene Therapy · 2021 · 16 citations

Life Sciences, Biotechnology, Molecular Biology +17