Regulation of endoplasmic reticulum turnover by selective autophagy

Aliaksandr Khaminets, Theresa Heinrich, Muriel Mari, +14

Nature

Cell AutophagyMitophagySelective AutophagySignal TransductionAutophagy +6

Transcriptional regulator PRDM12 is essential for human pain perception

Ya-Chun Chen, Michaela Auer‐Grumbach, Shinya Matsukawa, +56

Nature Genetics

Pain SyndromeSignal TransductionHealth SciencesPain MedicineMolecular Pain +6

Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis

Jan Ulrik Prause, Anand Goswami, István Katona, +10

Human Molecular Genetics

Abnormal ModificationAltered LocalizationProtein Quality ControlSystems BiologyAmyotrophic Lateral Sclerosis +13

Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy

Robert Fledrich, Tamer A. Abdelaal, Liam J. Rasch, +21

Nature Communications

Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice

Ágnes Patzkó, Yunhong Bai, Mario Saporta, +11

Brain

Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances

Jan Tilmann Vollrath, Antonio Sechi, Alice Dreser, +10

Cell Death and Disease

The ALS-linked E102Q mutation in Sigma receptor-1 leads to ER stress-mediated defects in protein homeostasis and dysregulation of RNA-binding proteins

Alice Dreser, Jan Tilmann Vollrath, Antonio Sechi, +16

Cell Death and Differentiation

Shortened internodal length of dermal myelinated nerve fibres in Charcot-Marie-Tooth disease type 1A

Mario Saporta, István Katona, Richard A. Lewis, +3

Brain

Cold-aggravated pain in humans caused by a hyperactive NaV1.9 channel mutant

Enrico Leipold, Andrea Hanson‐Kahn, M. Suzanne Frick, +11

Nature Communications

Small‐fiber neuropathy with cardiac denervation in postural tachycardia syndrome

Carl‐Albrecht Haensch, Marco Tosch, István Katona, +2

Muscle & Nerve