miRNAs reshape immunity and inflammatory responses in bacterial infection

Xikun Zhou, Xuefeng Li, Min Wu

Signal Transduction and Targeted Therapy

IL-37 Ameliorates the Inflammatory Process in Psoriasis by Suppressing Proinflammatory Cytokine Production

Xiu Teng, Zhonglan Hu, Xiaoqiong Wei, +17

The Journal of Immunology

Cutaneous KeratinocytesImmunologyImmune RegulationImmunologic MechanismInnate Immunity +17

Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation

Qingtian Li, Jia Zou, Mingjun Wang, +9

Nature Communications

ChromatinCell RegulationChromatin RemodelingNatural SciencesCritical Role +11

Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation

Zhen Wang, Hong Zhou, Huaping Zheng, +25

Autophagy

MicroRNA-302b augments host defense to bacteria by regulating inflammatory responses via feedback to TLR/IRAK4 circuits

Xikun Zhou, Xuefeng Li, Yan Ye, +5

Nature Communications

InflammationToll-like ReceptorsInflammatory ResponsesHost ResponseTlr/irak4 Circuits +7

Cancer-initiating cells derived from human rectal adenocarcinoma tissues carry mesenchymal phenotypes and resist drug therapies

CW Fan, Tong Chen, Y-N Shang, +13

Cell Death and Disease

Pseudomonas aeruginosa infection augments inflammation through miR-301b repression of c-Myb-mediated immune activation and infiltration

Xuefeng Li, Sisi He, Rongpeng Li, +7

Nature Microbiology

InflammationHost ResponseC-myb-mediated Immune ActivationBacterial InfectionsPathogenesis +9

Lyn Delivers Bacteria to Lysosomes for Eradication through TLR2-Initiated Autophagy Related Phagocytosis

Xuefeng Li, Sisi He, Xikun Zhou, +11

PLoS Pathogens

MitophagyInnate Immune SystemImmunologyExtracellular BacteriaAutophagosome Maturation +14

TesG is a type I secretion effector of Pseudomonas aeruginosa that suppresses the host immune response during chronic infection

Kelei Zhao, Wujiao Li, Jing Li, +18

Nature Microbiology

Host ResponseVirulence FactorPathogenesisImmunologyChronic Infection +8

Interleukin-37 promotes colitis-associated carcinogenesis via SIGIRR-mediated cytotoxic T cells dysfunction

Zhen Wang, Fanlian Zeng, Yawen Hu, +30

Signal Transduction and Targeted Therapy