Blair T. Lapointe

Strategy for Extending Half-life in Drug Design and Its Significance

Hakan Günaydin, Michael D. Altman, J. Michael Ellis et al. · ACS Medicinal Chemistry Letters · 2018 · 64 citations

Pharmaceutical Science, Pharmacotherapy, Biomedical Engineering +18

Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitors

Vladimir Simov, Sujal V. Deshmukh, Christopher J. Dinsmore et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 24 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +12

Discovery of <i>N</i>-(Indazol-3-yl)piperidine-4-carboxylic Acids as RORγt Allosteric Inhibitors for Autoimmune Diseases

Hongjun Zhang, Blair T. Lapointe, Neville J. Anthony et al. · ACS Medicinal Chemistry Letters · 2020 · 24 citations · Full text

Preparation of a Stable Trifluoroborate Salt for the Synthesis of 1-Aryl-2,2-difluoro-enolethers and/or 2,2-Difluoro-1-aryl-ketones via Palladium-Mediated Cross-Coupling

Jason D. Katz, Blair T. Lapointe, Christopher J. Dinsmore · The Journal of Organic Chemistry · 2009 · 21 citations

Cross-coupling Reaction, Heteroaryl Systems, Suitable Halide +8

Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1 <i>H</i> -Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease

David A. Candito, Vladimir Simov, Anmol Gulati et al. · Journal of Medicinal Chemistry · 2022 · 19 citations · Full text